Description

Bis(Trifluoromethyl)Chlorophosphine is a highly reactive organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its ability to introduce the bis(trifluoromethyl)phosphine group, a moiety prized for its unique electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing novel ligands, catalysts, and fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, especially those requiring fluorinated phosphine ligands for catalytic steps or as part of the active pharmaceutical ingredient (API).
• Agrochemical Synthesis: Serves as a key precursor for creating advanced fluorinated pesticides and herbicides with enhanced activity and environmental stability.
• Catalyst & Ligand Development: A fundamental starting material for synthesizing specialized phosphine ligands used in homogeneous catalysis, including cross-coupling and hydrogenation reactions.
• Fluorinated Polymer Research: Employed in the development of new fluorinated polymers and materials with specific thermal, chemical, or surface properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing phosphorus and fluorine atoms into complex organic molecules in research and development.
• Electronic Chemicals: Investigated for use in the deposition of thin films or as a precursor in the semiconductor industry for advanced material fabrication.

Basic Information

Product Name	Bis(Trifluoromethyl)Chlorophosphine
CAS No.	650-52-2
Molecular Formula	C2ClF6P
Molecular Weight	202.45 g/mol
Synonyms	Chlorobis(trifluoromethyl)phosphine; Bis(trifluoromethyl)phosphinous chloride; Phosphinous chloride, bis(trifluoromethyl)-; (Trifluoromethyl)phosphonous dichloride (related); P,P-Bis(trifluoromethyl)chlorophosphine; Chloro-bis(trifluoromethyl)phosphane
EINECS	211-476-5

Quality Control

Our Bis(Trifluoromethyl)Chlorophosphine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, GC, and GC-MS to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with global regulatory frameworks, and custom purity grades are available to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (argon or nitrogen) and allowed to equilibrate to room temperature before opening to prevent moisture ingress. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.