Description

Pentyl Chloroformate is a versatile and highly reactive alkyl chloroformate ester, a key reagent in organic synthesis. Its primary value lies in its role as an efficient alkoxycarbonylating agent, enabling the introduction of the pentyloxycarbonyl (Poc) protecting group and facilitating the synthesis of carbamates, carbonates, and other valuable intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to build complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the pentyloxycarbonyl (Poc) protecting group for amines and alcohols in multi-step drug synthesis.
• Agrochemical Production: Used in the manufacture of herbicides, fungicides, and insecticides, particularly in creating carbamate-based active ingredients.
• Polymer Chemistry: Serves as a monomer or modifying agent in the synthesis of polycarbonates and other specialty polymers.
• Peptide Synthesis: Employed as a coupling reagent and for N-protection strategies in solid-phase and solution-phase peptide chemistry.
• Chemical Derivatization: Utilized in analytical chemistry to derivative compounds for improved detection via GC or HPLC analysis.
• Organic Synthesis Reagent: A fundamental building block for preparing carbonates, urethanes, and other functionalized organic molecules.

Basic Information

Product Name	Pentyl Chloroformate
CAS No.	638-41-5
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	Amyl Chloroformate; n-Pentyl Chloroformate; Chloroformic Acid Pentyl Ester; Pentyl Carbonochloridate; n-Amyl Chloroformate; 1-Pentyl Chloroformate; Valeryl Chloroformate (obsolete); EINECS 211-340-6
EINECS	211-340-6

Quality Control

Our Pentyl Chloroformate is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC or titration and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, and relevant physical properties.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile and moisture-sensitive nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) at temperatures between 2°C and 8°C for long-term stability. Keep away from strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Acidity (as HCl)	≤ 0.5%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.05 - 1.07 g/mL
Refractive Index (n20D)	1.410 - 1.415

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.