Description

4-Phenylphenacyl Chloride is a versatile and high-value organic intermediate, primarily recognized for its role as a key building block in pharmaceutical synthesis. Its reactive acid chloride group makes it an essential precursor for the formation of esters, amides, and other complex molecular architectures. This compound is particularly critical for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce the 4-phenylphenacyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of compounds with specific aromatic ketone functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the phenacyl group is a key structural component.
• Fine Chemical Production: Serves as a precursor for various specialty chemicals, including dyes, photoinitiators, and polymer modifiers.
• Research & Development: Employed in organic synthesis laboratories for method development and the creation of novel chemical entities for screening.
• Ligand and Catalyst Preparation: Useful in the preparation of specialized ligands for metal catalysis or as a scaffold for catalyst design.

Basic Information

Product Name	4-Phenylphenacyl Chloride
CAS No.	635-84-7
Molecular Formula	C14H11ClO
Molecular Weight	230.69 g/mol
Synonyms	2-Chloro-1-(4-phenylphenyl)ethanone; p-Phenylphenacyl Chloride; 4-Benzoylbenzyl Chloride; (4-Phenylphenyl)chloroethanone; 2-Chloro-1-(4-biphenylyl)ethanone; 4-Biphenylylchloromethyl Ketone; α-Chloro-4-phenylacetophenone
EINECS	211-245-8

Quality Control

Our 4-Phenylphenacyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and loss on drying for moisture content, to ensure it meets stringent specifications for use as a high-purity intermediate. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.