Description

3-Methylbutyl Chloroformate is a versatile organic reagent belonging to the chloroformate ester family. This compound is primarily valued as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty polymers, where it acts as a protecting or activating agent. It is essential for research and production in fine chemical, pharmaceutical, and material science industries requiring high-purity building blocks.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in peptide coupling and carbamate formation.
• Agrochemical Synthesis: Serves as a key building block for producing herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Employed as a monomer or modifying agent in the production of polycarbonates, polyurethanes, and other specialty polymers.
• Chemical Derivatization: Utilized in analytical chemistry to derivative compounds for improved detection in gas chromatography (GC) or liquid chromatography (LC).
• Organic Synthesis Reagent: Acts as an efficient reagent for introducing the 3-methylbutyloxycarbonyl (Moc) protecting group in multi-step syntheses.
• Flavor & Fragrance Industry: Used in the controlled synthesis of specific esters that contribute to complex aroma profiles.

Basic Information

Product Name	3-Methylbutyl Chloroformate
CAS No.	628-50-2
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	Isoamyl Chloroformate; Isopentyl Chloroformate; 3-Methylbutyl Carbonochloridate; Chloroformic Acid Isoamyl Ester; Isoamyloxycarbonyl Chloride; Isopentyloxycarbonyl Chloride; (3-Methylbutoxy)carbonyl Chloride; NSC 60548
EINECS	211-043-6

Quality Control

Our 3-Methylbutyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong bases, amines, and alcohols. Due to its highly volatile and moisture-sensitive nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.02 - 1.04 g/mL
Refractive Index (n20D)	1.410 - 1.415

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.