Description

2-Methoxyethyl Chloroformate is a versatile and reactive chloroformate ester, a key intermediate in organic synthesis. Its primary value lies in its ability to act as a protecting group for alcohols and amines and as a reagent for introducing the 2-methoxyethoxycarbonyl moiety, facilitating the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to build active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protecting groups in peptide and carbohydrate chemistry.
• Agrochemical Synthesis: Serves as a key building block in the production of herbicides, insecticides, and fungicides.
• Polymer Chemistry: Employed as a monomer or modifying agent in the production of specialty polymers and polycarbonates.
• Chemical Research & Development: A valuable reagent in organic synthesis laboratories for creating novel compounds and conducting method development.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex colorants and functional dyes.
• Surface Modification Agent: Used to functionalize surfaces or materials with specific organic groups for enhanced properties.

Basic Information

Product Name	2-Methoxyethyl Chloroformate
CAS No.	628-12-6
Molecular Formula	C4H7ClO3
Molecular Weight	138.55 g/mol
Synonyms	2-Methoxyethyl carbonochloridate; Chloroformic acid 2-methoxyethyl ester; Ethanol, 2-methoxy-, 1-chloroformate; Methoxyethyl chloroformate; Methyl Cellosolve Chloroformate; 2-Methoxyethoxycarbonyl chloride; MOC-Cl; 628-12-6
EINECS	211-030-1

Quality Control

Our 2-Methoxyethyl Chloroformate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.18 - 1.22 g/mL
Refractive Index (n20D)	1.415 - 1.425

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.