Description

3-Chloropropionyl Chloride is a versatile and highly reactive acid chloride intermediate essential for organic synthesis. Its bifunctional nature, featuring both a reactive acyl chloride and a chlorinated alkyl chain, makes it a critical building block for constructing more complex molecules. This compound is primarily used by the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), herbicides, and functional polymers.

Application

• Pharmaceutical Synthesis: A key intermediate for producing a variety of drug molecules, including β-blockers and other cardiovascular agents.
• Agrochemical Manufacturing: Used in the synthesis of herbicides and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for specialty polymers and resins.
• Organic Synthesis: Acts as a versatile reagent for introducing the 3-chloropropionyl moiety in fine chemicals and complex organic compounds.
• Bioconjugation: Utilized in biochemical research for modifying proteins, peptides, and other biomolecules.
• Dye and Pigment Production: An intermediate in the manufacture of certain dyes and colorants.

Basic Information

Product Name	3-Chloropropionyl Chloride
CAS No.	625-36-5
Molecular Formula	C3H4Cl2O
Molecular Weight	126.97 g/mol
Synonyms	3-Chloropropanoyl Chloride; β-Chloropropionyl Chloride; 3-Chloropropanoic Acid Chloride; NSC 8815; β-Chloropropionyl Chloride; Chloropropionyl Chloride; Propionyl Chloride, 3-chloro-
EINECS	210-887-6

Quality Control

Our 3-Chloropropionyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We adhere to cGMP standards where applicable, and our quality management system is designed to meet the rigorous demands of the pharmaceutical and fine chemical industries. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, amines, and alcohols. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.