Description

1-[3-(Trifluoromethyl)Phenyl]Propanol-1 is a versatile fluorinated aromatic alcohol, serving as a crucial chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique properties imparted by the trifluoromethyl group, which can significantly alter the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides where the CF₃ group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Intermediate in the production of fluorinated components for electronic displays and organic light-emitting diodes, improving performance and stability.
• Chiral Ligand & Catalyst Development: Used in asymmetric synthesis to create novel ligands and organocatalysts for enantioselective reactions.
• Advanced Polymer Chemistry: Monomer or modifier for introducing fluorine into polymers to enhance chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: Versatile scaffold for medicinal chemistry, exploring structure-activity relationships (SAR) in drug discovery programs.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Propanol-1
CAS No.	618-97-3
Molecular Formula	C₁₀H₁₁F₃O
Molecular Weight	204.19 g/mol
Synonyms	3-(Trifluoromethyl)phenylpropanol; 1-(3-Trifluoromethylphenyl)-1-propanol; 3-(Trifluoromethyl)benzenepropanol; m-Trifluoromethylphenylpropyl alcohol; α-Ethyl-3-(trifluoromethyl)benzyl alcohol; 3'-(Trifluoromethyl)propiophenone, reduced; 1-Propanol, 1-[3-(trifluoromethyl)phenyl]-
EINECS	210-574-5

Quality Control

Our 1-[3-(Trifluoromethyl)Phenyl]Propanol-1 is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports compliance with REACH and other global regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.