Description

Bromhexine Hydrochloride CAS NO 611-75-6 is a synthetic derivative of vasicine, primarily recognized for its potent mucolytic and secretolytic properties. This active pharmaceutical ingredient (API) is critical for formulating effective respiratory therapeutics that help manage conditions characterized by excessive or viscous mucus. It is an essential raw material for pharmaceutical manufacturers producing cough syrups, tablets, and other dosage forms aimed at treating bronchitis, asthma, and chronic obstructive pulmonary disease (COPD).

Application

• Primary Active Pharmaceutical Ingredient (API) in cough suppressants and expectorants.
• Key component in the formulation of mucolytic tablets and syrups for respiratory relief.
• Used in the production of combination drugs for treating chronic bronchitis and associated airway disorders.
• Essential raw material in veterinary pharmaceuticals for treating respiratory conditions in animals.
• Intermediate in advanced pharmaceutical research for developing new respiratory therapies.
• Used in clinical settings for managing post-operative pulmonary complications.

Basic Information

Product Name	Bromhexine Hydrochloride
CAS No.	611-75-6
Molecular Formula	C14H21Br2N2 • HCl
Molecular Weight	412.60 g/mol
Synonyms	Bromhexine HCl; N-Cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine Hydrochloride; 2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemethanamine Hydrochloride; Bisolvon; Brovanexine; NA-274; Bromhexine Hydrochloride (USP); Bromhexini Hydrochloridum
EINECS	210-250-2

Quality Control

Our Bromhexine Hydrochloride is manufactured under strict quality management systems. Each batch is tested to meet or exceed relevant pharmacopoeial standards, including USP and EP monographs. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, related substances, residual solvents, and microbiological quality to ensure suitability for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in its original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.5% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbiological Quality	Meets USP <61> and <62> for non-sterile APIs

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.