Description

4-Amino-5-Cyano-7-(β-D-Ribofuranosyl)Pyrrolo[2,3-D]Pyrimidine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly those targeting RNA-based mechanisms. It is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the discovery of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analog antiviral drugs, such as certain RNA polymerase inhibitors.
• Anticancer Drug Research: Used in the development of novel chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid biochemistry.
• Pro-drug Development: Utilized in creating modified nucleosides with enhanced bioavailability or targeted delivery properties.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Chemical Biology Probes: Acts as a building block for labeled compounds used to study cellular processes and drug-target interactions.

Basic Information

Product Name	4-Amino-5-Cyano-7-(β-D-Ribofuranosyl)Pyrrolo[2,3-D]Pyrimidine
CAS No.	606-58-6
Molecular Formula	C₁₂H₁₃N₅O₄
Molecular Weight	291.26 g/mol
Synonyms	4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile; 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 4-amino-7-β-D-ribofuranosyl-; 4-Amino-5-cyano-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; Tubercidin-5-carbonitrile; 5-Cyano-4-amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 4-Amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile; 4-Amino-5-cyano-7-ribofuranosylpyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Cyano-7-(β-D-Ribofuranosyl)Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.