Description

Pregn-4-Ene-3,20-Dione,11,17-Dihydroxy-, (11A)- is a high-purity steroid intermediate, also known as 11α-Hydroxyprogesterone, which is critical for the synthesis of more complex corticosteroid and progestogen APIs. This compound matters for its role as a key chiral building block, enabling precise control over stereochemistry in downstream pharmaceutical manufacturing. It is primarily needed by research institutions and pharmaceutical companies engaged in the development and production of steroidal drugs, including anti-inflammatory agents and hormonal therapies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of corticosteroid active pharmaceutical ingredients (APIs).
• Steroid Research: Used as a reference standard and starting material in academic and industrial research exploring new steroidal compounds.
• Process Chemistry: Serves as a chiral template for developing and scaling up novel synthetic routes for complex hormone analogs.
• Fine Chemical Synthesis: Employed in the production of specialized progestogens and other high-value steroid derivatives.

Basic Information

Product Name	Pregn-4-Ene-3,20-Dione,11,17-Dihydroxy-, (11A)-
CAS No.	603-98-5
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	11α-Hydroxyprogesterone; 11α-Hydroxy-4-pregnene-3,20-dione; 11α-OH-P; 11α-Hydroxypregn-4-ene-3,20-dione; 11α-Hydroxyprogesteron; 11α-Hydroxyprogestérone; 11α-Hidroxiprogesterona; 11α-Idrossiprogesterone
EINECS	Contact for details

Quality Control

Our Pregn-4-Ene-3,20-Dione,11,17-Dihydroxy-, (11A)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (11α-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.