Description

3Beta,17,21-Trihydroxy-5Beta-Pregnan-20-One is a key steroid intermediate with significant importance in pharmaceutical synthesis. This compound serves as a crucial precursor in the production of various corticosteroid and hormonal APIs, enabling the development of essential therapeutic agents. It is primarily required by pharmaceutical manufacturers and research institutions engaged in steroid chemistry and advanced drug development.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of corticosteroids like hydrocortisone and its derivatives.
• API Synthesis: Used in the multi-step production of active pharmaceutical ingredients (APIs) for anti-inflammatory and immunosuppressive medications.
• Biochemical Research: Employed as a reference standard and starting material in steroid metabolism and endocrinology studies.
• Process Development: Utilized in R&D for developing and scaling up new synthetic routes for steroid-based drugs.
• Fine Chemical Production: Serves as a high-purity intermediate for manufacturers of specialty and fine chemicals.

Basic Information

Product Name	3Beta,17,21-Trihydroxy-5Beta-Pregnan-20-One
CAS No.	601-03-6
Molecular Formula	C21H34O4
Molecular Weight	350.49 g/mol
Synonyms	5β-Pregnane-3β,17α,21-triol-20-one; 3β,17α,21-Trihydroxy-5β-pregnan-20-one; 17α,21-Dihydroxy-3β-hydroxy-5β-pregnan-20-one; Tetrahydro Compound S; 5β-Tetrahydro Compound S; 3β,17α,21-Trihydroxy-5β-pregnan-20-one; 5β-Pregnan-3β,17α,21-triol-20-one; 3β,17α,21-Trihydroxy-5β-pregnane-20-one
EINECS	Contact for details

Quality Control

Our 3Beta,17,21-Trihydroxy-5Beta-Pregnan-20-One is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC and spectroscopic methods, to ensure high purity and consistency suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.