Description

3,3',5,5'-Tetraiodothyro-Acetic Acid is a high-purity iodinated thyronine derivative, a key intermediate in pharmaceutical research and development. This compound is valued for its structural role in the synthesis of thyroid hormone analogs and related bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies focused on endocrinology, metabolic disorder therapeutics, and advanced diagnostic agent development.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of thyroid hormone analogs and receptor ligands.
• Biochemical Research: Used as a reference standard or probe in studies of thyroid hormone action, metabolism, and transport mechanisms.
• Diagnostic Agent Development: Serves as a precursor in the development of radiolabeled compounds for diagnostic imaging.
• Endocrinology Studies: Employed in in vitro and in vivo research to investigate hormonal pathways and metabolic functions.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	3,3',5,5'-Tetraiodothyro-Acetic Acid
CAS No.	67-30-1
Molecular Formula	C14H8I4O4
Molecular Weight	777.83 g/mol
Synonyms	TETRAC; 3,3',5,5'-Tetraiodothyroacetic Acid; Acide Tetraiodothyroacetique; Tetraiodothyroacetic Acid; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Acetic Acid; TA4; Tetramet; Thyroacetic Acid, Tetraiodo-; NSC 14757
EINECS	200-653-6

Quality Control

Our 3,3',5,5'-Tetraiodothyro-Acetic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.