Description

Strophanthidin is a potent cardiac glycoside aglycone derived from plants of the *Strophanthus* genus. This high-purity reference standard is critical for pharmaceutical research, particularly in the study of cardiac pharmacology and sodium-potassium ATPase inhibition. It serves as an essential intermediate and analytical standard for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors requiring precise and reliable bioactive compounds.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for quality control and assay development of cardiac glycoside-based drugs.
• Biochemical Research: Key tool for in vitro studies investigating the mechanism of action of cardiotonic steroids on the Na+/K+-ATPase pump.
• Metabolite and Impurity Analysis: Used in analytical laboratories (HPLC, LC-MS) for the identification and quantification of strophanthidin as a metabolite or degradation product of related glycosides like ouabain.
• Precursor for Semisynthesis: Serves as a core aglycone structure for the chemical synthesis and modification of novel cardiac-active compounds.
• Academic and Clinical Research: Employed in university and institutional labs for cardiovascular disease research and pharmacological profiling.

Basic Information

Product Name	Strophanthidin
CAS No.	66-28-4
Molecular Formula	C23H32O6
Molecular Weight	404.50 g/mol
Synonyms	3β,5,14-Trihydroxy-19-oxo-5β-card-20(22)-enolide; Strophanthidine; Strofantidina; Strophanthidol 19-aldehyde; NSC 406180; (3β,5β)-3,5,14-Trihydroxy-19-oxocard-20(22)-enolide; 5β-Strophanthidin; 3β,5β,14β-Trihydroxy-19-oxo-5β,14β-card-20(22)-enolide
EINECS	200-625-8

Quality Control

Our Strophanthidin is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We adhere to relevant industry guidelines for reference standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.