Description

3-Acetyl Strophanthidin is a key acetylated derivative of the cardiac glycoside strophanthidin. This compound is of significant interest in pharmaceutical research and development, particularly for its role as a synthetic intermediate and reference standard. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular drug discovery and biochemical studies. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D and analytical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel cardiac glycoside derivatives and related therapeutic agents.
• Biochemical Research: Used as a reference standard and tool compound in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac pharmacology.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for method development, calibration, and quality control of related substances.
• Academic Research: Utilized in university and institutional labs for fundamental research on steroid chemistry, glycoside structure-activity relationships, and molecular biology pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and process development.

Basic Information

Product Name	3-Acetyl Strophanthidin
CAS No.	60-38-8
Molecular Formula	C25H34O7
Molecular Weight	446.53 g/mol
Synonyms	3-Acetylstrophanthidin; 3β-Acetoxy-5β,14β-dihydroxy-19-oxo-card-20(22)-enolide; Strophanthidin 3-acetate; 3-O-Acetylstrophanthidin; Acetylstrophanthidin; 3-Acetoxystrophanthidin; 3-Acetyl-strophanthidin; 3β-Acetoxy-5β,14β-dihydroxy-19-oxocard-20(22)-enolide
EINECS	200-483-6

Quality Control

Our 3-Acetyl Strophanthidin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.