Description

Hexamethonium Chloride is a bis-quaternary ammonium salt compound, widely recognized for its potent ganglionic blocking activity. This pharmacological property makes it a valuable research-grade chemical for studying autonomic nervous system function and hypertension. It serves as a critical tool compound for pharmaceutical R&D, academic research, and chemical synthesis. Our supply ensures high purity and batch-to-batch consistency for reliable experimental results.

Application

• Pharmacological Research: Used as a standard ganglionic blocking agent in preclinical studies to investigate autonomic nervous system pathways and cardiovascular physiology.
• Biochemical Assay Development: Serves as a reference standard or active control in the development and validation of assays targeting nicotinic acetylcholine receptors (nAChRs).
• Academic & Institutional Research: A key reagent for university and institutional labs studying neurotransmission, smooth muscle contraction, and the mechanisms of blood pressure regulation.
• Chemical Intermediate: Utilized in organic synthesis for the preparation of other quaternary ammonium compounds or specialized ionic materials.
• Reference Standard: Supplied as a high-purity material for use as an analytical standard in quality control laboratories.

Basic Information

Product Name	Hexamethonium Chloride
CAS No.	60-26-4
Molecular Formula	C12H30Cl2N2
Molecular Weight	273.28 g/mol
Synonyms	Hexamethonium Dichloride; 1,6-Hexanebis(trimethylammonium) Chloride; Hexamethylene-1,6-bis(trimethylammonium) Dichloride; Esametonio Cloruro; Hexametonium Chloride; NSC 7576; Hexamethone Chloride; Bis(trimethylammonium)hexane Dichloride
EINECS	200-473-4

Quality Control

Our Hexamethonium Chloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.