Description

Hexamethonium Chloride is a bis-quaternary ammonium compound widely recognized for its potent ganglionic blocking activity. This property makes it a valuable research chemical and a key reference standard in pharmacological and physiological studies. It is primarily utilized by researchers in the pharmaceutical, academic, and biotechnology sectors investigating autonomic nervous system function, hypertension, and the mechanisms of neuromuscular transmission.

Application

• Pharmacological Research: As a classic nicotinic acetylcholine receptor (nAChR) antagonist at autonomic ganglia for studying neurotransmission and blood pressure regulation.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control in pharmaceutical analysis.
• Physiological Studies: Employed in experimental models to induce controlled hypotension and to investigate the role of the sympathetic nervous system.
• Biochemical Research: As a tool compound to explore ion channel function and receptor-ligand interactions in vitro.
• Academic & Educational Use: Serves as a teaching aid in university laboratories for advanced pharmacology and physiology courses.

Basic Information

Product Name	Hexamethonium Chloride
CAS No.	60-25-3
Molecular Formula	C12H30Cl2N2
Molecular Weight	273.28 g/mol
Synonyms	Hexamethonium Dichloride; Hexamethylene-1,6-bis(trimethylammonium) Dichloride; Esametonio Cloruro; Esametônio Cloreto; Hexametonium Chloride; Hexonium; Vegolysen; Methium
EINECS	200-473-4

Quality Control

Our Hexamethonium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade specifications suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.