Description

Benzene, 1-Chloro-2-Fluoro-4-Isothiocyanato- (9Ci) is a specialized aromatic building block featuring a reactive isothiocyanate functional group. This compound is valued for its role as a key intermediate in the synthesis of more complex heterocyclic and pharmaceutical molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those containing benzothiazole or thiourea moieties.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its reactive site for structural diversification.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic framework (MOF) construction.
• Fluorescent Probe Development: Acts as a starting material for creating isothiocyanate-derived fluorescent dyes and labeling reagents used in bioimaging.
• Polymer Modification: Utilized to introduce functional groups into polymer backbones to alter material properties like adhesion or biocompatibility.
• Chemical Biology Tool: Functions as a protein-labeling agent due to the reactivity of the isothiocyanate group with amine functionalities.

Basic Information

Product Name	Benzene, 1-Chloro-2-Fluoro-4-Isothiocyanato- (9Ci)
CAS No.	597545-17-0
Molecular Formula	C7H3ClFNS
Molecular Weight	187.62 g/mol
Synonyms	1-Chloro-2-fluoro-4-isothiocyanatobenzene; 4-Isothiocyanato-1-chloro-2-fluorobenzene; 2-Fluoro-4-isothiocyanato-1-chlorobenzene; 1-Chloro-2-fluoro-4-isothiocyanato-benzene; (2-Fluoro-4-isothiocyanatophenyl) chloride; 4-Chloro-3-fluorophenyl isothiocyanate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Benzene, 1-Chloro-2-Fluoro-4-Isothiocyanato- (9Ci) is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific chromatographic and spectroscopic results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.