Description

1H-1-Benzazepine-1-Carbonyl Chloride, 2,3,4,5-Tetrahydro- (9Ci) is a high-purity, reactive chemical intermediate belonging to the benzazepine class of heterocyclic compounds. This compound is of significant value for its role as a key building block in the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Material Science Research: Employed in the development of specialty polymers and organic electronic materials due to its fused ring structure.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and scale-up projects.

Basic Information

Product Name	1H-1-Benzazepine-1-Carbonyl Chloride, 2,3,4,5-Tetrahydro- (9Ci)
CAS No.	585578-15-0
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	2,3,4,5-Tetrahydro-1H-1-benzazepine-1-carbonyl chloride; 1H-1-Benzazepine-1-carbonyl chloride, 2,3,4,5-tetrahydro-; Tetrahydrobenzazepine-1-carbonyl chloride; 1-Carbamoyl-2,3,4,5-tetrahydro-1H-1-benzazepine chloride; Benzazepine carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our 1H-1-Benzazepine-1-Carbonyl Chloride, 2,3,4,5-Tetrahydro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.