Description

1-[(2S)-2-[(7-Chlorobenzo[B]Thien-3-Yl)Methoxy]-2-(2,4-Dichlorophenyl)Ethyl]-1H-Imidazole is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the discovery and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of novel drug candidates, particularly in antifungal and other therapeutic classes.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for the research and scale-up of new chemical entities (NCEs).
• Biochemical Research: Used as a reference standard or probe compound in pharmacological and metabolic studies.
• Process Chemistry & Route Scouting: Employed by process chemists to develop and optimize scalable, cost-effective synthetic pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	1-[(2S)-2-[(7-Chlorobenzo[B]Thien-3-Yl)Methoxy]-2-(2,4-Dichlorophenyl)Ethyl]-1H-Imidazole
CAS No.	583057-51-6
Molecular Formula	C20H15Cl3N2OS
Molecular Weight	437.77 g/mol
Synonyms	(2S)-1-(7-Chlorobenzo[b]thien-3-yl)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol; 1-[(2S)-2-[(7-Chlorobenzo[B]Thien-3-Yl)Methoxy]-2-(2,4-Dichlorophenyl)Ethyl]-1H-Imidazole; (S)-1-(7-Chlorobenzo[b]thiophen-3-yl)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol; UNII-9J8H6W6H4C; 9J8H6W6H4C; SCHEMBL218042; BCP31833; AGN-PC-0JSTPJ
EINECS	Contact for details

Quality Control

Our 1-[(2S)-2-[(7-Chlorobenzo[B]Thien-3-Yl)Methoxy]-2-(2,4-Dichlorophenyl)Ethyl]-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-enantiomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.