Description

Arasertaconazole is a potent and highly selective antifungal agent belonging to the triazole class of compounds. Its primary value lies in its targeted mechanism of action, which inhibits fungal ergosterol biosynthesis, making it a critical active pharmaceutical ingredient (API) for advanced therapeutic formulations. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for systemic and topical fungal infections.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of antifungal medications.
• Key intermediate in the synthesis of novel triazole-based antifungal agents.
• Reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Research and development of treatments for invasive aspergillosis and candidiasis.
• Development of topical creams and ointments for dermatological fungal infections.
• Investigational compound in preclinical studies for its antimicrobial efficacy.

Basic Information

Product Name	Arasertaconazole
CAS No.	583057-48-1
Molecular Formula	C20H17F2N5O2S
Molecular Weight	445.45 g/mol
Synonyms	AZD 4818; Arasertaconazole Nitrate; (2R,3R)-2-(2,4-Difluorophenyl)-3-(5-{[(1R)-1-(1H-1,2,4-triazol-1-yl)ethyl]thio}-4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; (2R,3R)-3-[4-Fluoro-5-({(1R)-1-[1,2,4]triazol-1-yl-ethyl}sulfanyl)-phenyl]-2-(2,4-difluoro-phenyl)-1-(1H-[1,2,4]triazol-1-yl)-butan-2-ol
EINECS	Contact for details

Quality Control

Our Arasertaconazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting compliance with relevant standards are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.