Description

Benzenemethanol, 3,5-Difluoro-α-Methyl-, (+)- (9Ci) is a high-purity, chiral fluorinated benzyl alcohol derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and fluorine atoms into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel, potent herbicides and pesticides with improved metabolic stability and bioavailability.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the development of specialty polymers and liquid crystals with unique optical or electronic properties.
• Academic & Industrial R&D: Used in methodological studies and process chemistry for introducing fluorinated, chiral benzyl motifs.

Basic Information

Product Name	Benzenemethanol, 3,5-Difluoro-α-Methyl-, (+)- (9Ci)
CAS No.	575488-41-4
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(+)-3,5-Difluoro-α-methylbenzyl alcohol; (R)-3,5-Difluoro-α-methylbenzyl alcohol; (R)-1-(3,5-Difluorophenyl)ethanol; 1-(3,5-Difluorophenyl)ethan-1-ol (enantiomer); Benzenemethanol, 3,5-difluoro-α-methyl-, (αR)-; (R)-3,5-Difluoro-α-methylbenzenemethanol; 575488-41-4
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, 3,5-Difluoro-α-Methyl-, (+)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure consistent high quality and enantiomeric excess (e.e.) suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral assay are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.