Description

5-Methyl-1-benzothiophene-2-carbonyl chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound serves as a critical building block for constructing complex heterocyclic molecules, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the benzothiophene core for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic semiconductors, conductive polymers, and specialty dyes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Ligand and Catalyst Development: Acts as a foundational structure for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5-Methyl-1-benzothiophene-2-carbonyl chloride
CAS No.	568577-85-5
Molecular Formula	C11H9ClOS
Molecular Weight	224.70 g/mol
Synonyms	5-Methylbenzo[b]thiophene-2-carbonyl chloride; 2-(Chlorocarbonyl)-5-methyl-1-benzothiophene; 5-Methyl-1-benzothiophene-2-carboxylic acid chloride; 5-Methylbenzothiophene-2-carbonyl chloride; 5-Methylbenzo[b]thiophene-2-carboxylic acid chloride; 5-Methyl-1-benzothiophene-2-carboxyl chloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-1-benzothiophene-2-carbonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.