Description

N6,N6-Dimethyl-3'-β-C-Methyl- Adenosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside-based chemistry. The product, identified by CAS No. 565450-85-3, is supplied with a commitment to high purity and batch-to-batch consistency to support rigorous scientific work.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of modified nucleoside prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Research: Used in the development of nucleotide analogs targeting viral polymerases for potential treatments against hepatitis C (HCV) and other viral infections.
• Oncology Drug Discovery: Investigated as a precursor for compounds designed to inhibit cancer cell proliferation by interfering with RNA synthesis or function.
• Biochemical Research: Serves as a tool compound in enzymatic studies, particularly those involving adenosine-processing enzymes, to understand inhibition mechanisms.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and NMR analyses.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside-derived drug candidates.

Basic Information

Product Name	N6,N6-Dimethyl-3'-β-C-Methyl- Adenosine
CAS No.	565450-85-3
Molecular Formula	C13H19N5O4
Molecular Weight	309.32 g/mol
Synonyms	3'-C-Methyl-N6,N6-dimethyladenosine; 3'-β-C-Methyl-N6,N6-dimethyladenosine; 1-(3-C-Methyl-β-D-ribofuranosyl)-N6,N6-dimethyladenine; 3'-C-Me-N6,N6-dimethyladenosine; 2'-Deoxy-2'-C-methyl-N6,N6-dimethyladenosine (related isomer); 3'-Methyl-N6,N6-dimethyladenosine; N6,N6-Dimethyl-3'-C-methyladenosine; 565450-85-3
EINECS	Contact for details

Quality Control

Our N6,N6-Dimethyl-3'-β-C-Methyl- Adenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions (e.g., under nitrogen or argon) at a controlled room temperature (15-25°C). For long-term storage, desiccants are recommended. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.