Description

N6,N6-Dimethyl-2'-C-Methyladenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and study of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in antiviral, anticancer, and metabolic disease research programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of modified nucleotides and nucleoside-based prodrugs.
• Antiviral Research: Used in the development and study of antiviral compounds targeting RNA viruses.
• Oncology Research: Serves as a scaffold for investigating novel anticancer agents that interfere with cellular nucleic acid metabolism.
• Biochemical Tool: Acts as a reference standard and substrate in enzymatic studies and metabolic pathway analysis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) in GMP environments.

Basic Information

Product Name	N6,N6-Dimethyl-2'-C-Methyladenosine
CAS No.	565450-77-3
Molecular Formula	C13H19N5O4
Molecular Weight	309.32 g/mol
Synonyms	2'-C-Methyl-N6,N6-dimethyladenosine; 2'-C-Methyl-6-(dimethylamino)purine riboside; 6-(Dimethylamino)-2'-C-methylpurine ribonucleoside; 9-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl)-6-(dimethylamino)purine; 2'-C-Methyl-6-dimethylaminopurine riboside; N6,N6-Dimethyl-2'-methyladenosine; 2'-Methyl-N6,N6-dimethyladenosine
EINECS	Contact for details

Quality Control

Our N6,N6-Dimethyl-2'-C-Methyladenosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.