Description

Cedirannib CAS NO 557795-03-6 is a high-purity, small molecule pharmaceutical intermediate and research chemical. This compound is of significant value for its role in the development and synthesis of targeted therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or active compound in enzymatic assays and cellular pathway studies.
• Preclinical Development: Serves as a critical material for formulation studies, pharmacokinetic (PK) and pharmacodynamic (PD) research.
• Academic Research: Employed in university and institutional labs for investigating signal transduction mechanisms and drug discovery projects.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and GMP production.

Basic Information

Product Name	Cedirannib
CAS No.	557795-03-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea; Cediranib Impurity; AZD2171 Impurity; AZD 2171 Related Compound; 4-[4-(3-Amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea; Cediranib Intermediate; Cediranib Related Substance
EINECS	Contact for details

Quality Control

Our Cedirannib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.