Description

3-Buten-2-One, 4-(Ethylamino)-1,1,1-Trifluoro- is a specialized fluorinated organic building block featuring a reactive enone moiety and an ethylamino substituent. This compound matters as a versatile intermediate for synthesizing complex molecules, particularly in the development of pharmaceuticals and agrochemicals where the trifluoromethyl group is a key structural motif for enhancing metabolic stability and bioavailability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology, leveraging the trifluoromethyl group's properties.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, or organic electronic materials that require specific fluorinated components for enhanced performance.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development, exploring new fluorination reactions, and creating compound libraries for screening.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing bespoke fluorinated compounds for client-specific projects.

Basic Information

Product Name	3-Buten-2-One, 4-(Ethylamino)-1,1,1-Trifluoro-
CAS No.	538308-78-0
Molecular Formula	C7H10F3NO
Molecular Weight	181.16 g/mol
Synonyms	4-(Ethylamino)-1,1,1-trifluoro-3-buten-2-one; 1,1,1-Trifluoro-4-(ethylamino)-3-buten-2-one; 4-Ethylamino-1,1,1-trifluorobut-3-en-2-one; N-Ethyl-4,4,4-trifluoro-3-oxobut-1-en-1-amine; (E/Z)-4-(Ethylamino)-1,1,1-trifluorobut-3-en-2-one; Ethyl-(4,4,4-trifluoro-3-oxobut-1-enyl)amine; TFBO-EA
EINECS	Contact for details

Quality Control

Our 3-Buten-2-One, 4-(Ethylamino)-1,1,1-Trifluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.