Description

2-Fluoro-6-Methylbenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in introducing both the benzoyl chloride and a strategically placed fluorine substituent into target molecules, enabling precise control over molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated aromatic cores in electronic and display materials, improving charge transport and thermal stability.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorinated benzoyl groups into polymer chains, altering surface properties and chemical resistance.
• Organic Synthesis Reagent: A fundamental reagent for Friedel-Crafts acylation, amide coupling, and esterification reactions in research and development laboratories.
• Dye & Pigment Manufacturing: Intermediate for creating specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2-Fluoro-6-Methylbenzoyl Chloride
CAS No.	535961-78-5
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Fluoro-6-methylbenzoyl chloride; 2-Fluoro-6-methylbenzoic acid chloride; o-Fluoro-o-toluoyl chloride; 6-Fluoro-2-methylbenzoyl chloride; 2-Methyl-6-fluorobenzoyl chloride; (2-Fluoro-6-methylphenyl)carbonyl chloride; Benzoyl chloride, 2-fluoro-6-methyl-; 535961-78-5
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.