Description

(R)-o-Acetyl-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is a high-value, chiral fluorinated intermediate of significant importance in modern synthetic chemistry. Its core value proposition lies in its unique molecular architecture, featuring a stereogenic center and electron-deficient trifluoromethyl groups, which makes it indispensable for constructing complex bioactive molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in areas like oncology, CNS disorders, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals that require fluorinated aromatic components for specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Item	Details
Product Name	(R)-o-Acetyl-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
CAS No.	534613-13-3
Molecular Formula	C12H10F6O2
Molecular Weight	300.20 g/mol
Synonyms	(R)-1-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxyethyl acetate; (R)-1-(3,5-Bis(trifluoromethyl)phenyl)-2-hydroxyethyl acetate; (R)-α-Acetoxy-3,5-bis(trifluoromethyl)benzeneethanol; (R)-2-Acetoxy-1-[3,5-bis(trifluoromethyl)phenyl]ethanol; (R)-O-Acetyl-1-(3,5-bis(trifluoromethyl)phenyl)ethanol; (R)-1-(3,5-Bis(trifluoromethyl)phenyl)-2-acetoxyethanol
EINECS	Contact for details

Quality Control

Our (R)-o-Acetyl-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production use. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to verify identity, potency, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.