Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-n-(4-Isothiocyanatophenyl)-2-Oxo-, (3As,4S,6Ar)- is a high-purity, complex heterocyclic compound with significant potential in advanced pharmaceutical research and development. This specialized chemical serves as a critical building block or intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex molecular architectures.
• Bioconjugation & Probe Development: The reactive isothiocyanate (-NCS) group enables its use in labeling proteins, antibodies, or other biomolecules for diagnostic assays and research probes.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to explore new pharmacophores and optimize drug-like properties.
• Chemical Biology Tool: Employed in the development of enzyme inhibitors or receptor modulators for pathway analysis and target validation.
• Advanced Material Synthesis: Potential use as a monomer or functional component in the development of specialized polymers or organic electronic materials.

Basic Information

Item	Details
Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-n-(4-Isothiocyanatophenyl)-2-Oxo-, (3As,4S,6Ar)-
CAS No.	525583-47-5
Molecular Formula	C18H20N4O2S2
Molecular Weight	388.51 g/mol
Synonyms	Hexahydro-N-(4-isothiocyanatophenyl)-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; (3aS,4S,6aR)-Hexahydro-N-(4-isothiocyanatophenyl)-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; Biotin-isothiocyanate derivative; Biotin-NCS; Biotin isothiocyanate analog; 4-Pentanamide, 1H-thieno[3,4-d]imidazole-4-, hexahydro-N-(4-isothiocyanatophenyl)-2-oxo-, (3aS,4S,6aR)-
EINECS	Contact for details

Quality Control

Our 1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-n-(4-Isothiocyanatophenyl)-2-Oxo-, (3As,4S,6Ar)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.