Description

Zd 6474 Hydrochloride is a high-purity small molecule compound, also known by its CAS number 524722-52-9. This product is a critical pharmaceutical intermediate and research chemical, valued for its consistent quality and reliable performance in demanding applications. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in oncology and targeted therapy research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a potent and selective inhibitor in kinase signaling pathway studies and cancer research.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in laboratories.
• Preclinical Development: Utilized in in-vitro and in-vivo studies for evaluating drug efficacy and mechanism of action.
• Fine Chemical Synthesis: Acts as a specialized reagent for constructing complex molecular architectures in organic chemistry.

Basic Information

Product Name	Zd 6474 Hydrochloride
CAS No.	524722-52-9
Molecular Formula	C22H24ClFN4O • HCl
Molecular Weight	475.81 g/mol
Synonyms	Vandetanib Hydrochloride; ZD-6474 Hydrochloride; Zactima Hydrochloride; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine Hydrochloride; Caprelsa (Vandetanib) Impurity; ZD6474 HCl; AZD-6474 Hydrochloride; UNII-090T4BQ92M
EINECS	Contact for details

Quality Control

Our Zd 6474 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific pharmacopeial or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.