Description

5-(4-Chloro-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel pyrazolopyrimidine-based active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific biological activity.
• Chemical Synthesis: Serves as a versatile reagent for introducing the pyrazolo[1,5-a]pyrimidine moiety into more complex molecular architectures.
• Material Science: Potential precursor for creating specialty polymers or organic electronic materials with unique properties.
• Biochemical Tool Compound: Used in life science research to study enzyme inhibition and cellular signaling pathways.

Basic Information

Product Name	5-(4-Chloro-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride
CAS No.	522600-26-6
Molecular Formula	C14H6Cl2F3N3O
Molecular Weight	376.12 g/mol
Synonyms	5-(4-Chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 5-(p-Chlorophenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 522600-26-6; Pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 5-(4-chlorophenyl)-7-(trifluoromethyl)-; 5-(4-Chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-(4-Chloro-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.