Description

Thiocyanic Acid, (1R,4R)-3,3-Dimethyl-2-Methylenebicyclo[2.2.1]Hept-1-Yl Ester (9Ci) is a specialized chiral thiocyanate derivative based on a rigid, camphor-like bicyclic framework. This compound is valued as a high-purity chemical intermediate for its unique steric and electronic properties imparted by the bornane skeleton. It is primarily utilized in advanced organic synthesis and pharmaceutical research, where precise molecular architecture is critical for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the thiocyanate functional group and chiral backbone can contribute to biological activity.
• Ligand and Catalyst Synthesis: Acts as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science: Investigated for incorporation into advanced polymers or as a modifying agent to impart specific chemical functionalities to surfaces.
• Flavor and Fragrance Chemistry: Potential intermediate for synthesizing high-value aroma chemicals with complex, terpene-like structures.
• Academic and R&D: A valuable reagent for methodological studies in organic synthesis, including cycloaddition reactions and stereoselective transformations.

Basic Information

Product Name	Thiocyanic Acid, (1R,4R)-3,3-Dimethyl-2-Methylenebicyclo[2.2.1]Hept-1-Yl Ester (9Ci)
CAS No.	521068-33-7
Molecular Formula	C11H15NS
Molecular Weight	193.31 g/mol
Synonyms	(1R,4R)-1-Isothiocyanato-3,3-dimethyl-2-methylenebicyclo[2.2.1]heptane; (1R,4R)-3,3-Dimethyl-2-methylenenorbornan-1-yl isothiocyanate; (+)-Bornyl isothiocyanate; (1R,4R)-2-Methylene-3,3-dimethylbicyclo[2.2.1]heptan-1-yl thiocyanate; NSC 836906; 1-Isothiocyanato-3,3-dimethyl-2-methylenenorbornane (stereo); Thiocyanic acid, born-2-en-10-yl ester (related); Bicyclo[2.2.1]heptane, 1-isothiocyanato-3,3-dimethyl-2-methylene-, (1R,4R)-
EINECS	Contact for details

Quality Control

Our production of Thiocyanic Acid, (1R,4R)-3,3-Dimethyl-2-Methylenebicyclo[2.2.1]Hept-1-Yl Ester adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chemical purity and chiral integrity, critical for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.