Description

1H-Pyrazole-5-Carbonyl Chloride, 1-Methyl-3-Nitro- (9Ci) is a high-value, reactive chemical intermediate characterized by its nitro-substituted pyrazole core and an acid chloride functional group. This compound matters for its role as a critical building block in the synthesis of more complex heterocyclic molecules, enabling the introduction of the 1-methyl-3-nitropyrazole moiety. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders and inflammation.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides by serving as a core heterocyclic scaffold.
• Material Science Research: Employed in the development of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1H-Pyrazole-5-Carbonyl Chloride, 1-Methyl-3-Nitro- (9Ci)
CAS No.	519165-02-7
Molecular Formula	C5H4ClN3O3
Molecular Weight	189.56 g/mol
Synonyms	1-Methyl-3-nitro-1H-pyrazole-5-carbonyl chloride; 1-Methyl-3-nitropyrazole-5-carbonyl chloride; 3-Nitro-1-methyl-1H-pyrazole-5-carbonyl chloride; 5-Carbonyl chloride-1-methyl-3-nitropyrazole; 1-Methyl-3-nitro-5-pyrazolecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrazole-5-Carbonyl Chloride, 1-Methyl-3-Nitro- (9Ci) is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are essential for your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.