Description

Tasisulam CAS NO 519055-62-0 is a potent small molecule compound belonging to the sulfonamide class, designed as a targeted anti-cancer agent. Its primary value lies in its unique mechanism of action, which involves the induction of apoptosis and disruption of tumor cell metabolism, making it a candidate for oncology research and development. This product is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutic strategies for solid tumors and hematological malignancies.

Application

• Oncology Research & Drug Discovery: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical studies for investigating novel cancer therapies.
• Biochemical Assay Development: Used in high-throughput screening (HTS) and in vitro assays to study mechanisms of apoptosis and cell cycle arrest.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling: Employed as a calibrant in analytical method development (e.g., LC-MS/MS) for drug metabolism studies.
• Target Validation Studies: A critical tool for validating specific molecular targets involved in cancer cell survival and proliferation pathways.
• Formulation Research: Used in the development and testing of various drug delivery systems, such as liposomal or nanoparticle formulations.
• Academic & Clinical Research: Supports fundamental research into the biology of cancer and the evaluation of combination therapies in experimental models.

Basic Information

Product Name	Tasisulam
CAS No.	519055-62-0
Molecular Formula	C₁₇H₁₄BrN₃O₄S₂
Molecular Weight	476.35 g/mol
Synonyms	LY-573636; N-[3-Bromo-4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenyl]-4-methylbenzenesulfonamide; Tasisulam sodium; Benzenesulfonamide, N-[3-bromo-4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenyl]-4-methyl-; LY573636; LY 573636
EINECS	Contact for details

Quality Control

Our Tasisulam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing results for assay, related substances, residual solvents, and other critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.