Description

17-Azido-3,6,9,12,15-Pentaoxaheptadecan-1-Amine is a specialized bifunctional linker molecule featuring a reactive amine group and a terminal azide, connected by a hydrophilic polyethylene glycol (PEG) spacer. This compound is engineered for high-value applications in bioconjugation and materials science, enabling the stable and site-specific attachment of biomolecules or functional groups via click chemistry. It is essential for researchers and manufacturers in the pharmaceutical, diagnostics, and advanced polymer sectors who require reliable, high-purity building blocks for creating novel conjugates, hydrogels, and surface modifications.

Application

• Bioconjugation and Protein/Peptide Labeling: The amine group allows for coupling to carboxylates or carbonyls, while the azide enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for attaching fluorescent dyes, drugs, or other probes.
• PEGylation Reagent: Used to introduce a hydrophilic PEG chain onto drugs, proteins, or nanoparticles to improve solubility, reduce immunogenicity, and enhance circulation time in vivo.
• Polymer and Dendrimer Synthesis: Serves as a versatile monomer or cross-linking agent for creating functionalized polymers, smart hydrogels, and dendrimers with tailored properties.
• Surface Functionalization: Applied to modify the surface of chips, sensors, beads, or medical devices with amine or azide groups for subsequent biomolecule immobilization.
• Diagnostic Assay Development: Utilized in the construction of immunoassays, biosensors, and other diagnostic platforms where controlled orientation of capture molecules is critical.
• Antibody-Drug Conjugate (ADC) Linker Research: Investigated as a component in the design of novel cleavable or non-cleavable linkers for targeted cancer therapies.
• Materials for Drug Delivery Systems: Incorporated into the matrix of nanoparticles, micelles, or liposomes to enable targeted drug release or specific cell uptake mechanisms.
• Click Chemistry Tool for Chemical Biology: A fundamental reagent for metabolic labeling, activity-based protein profiling, and other bioorthogonal chemistry applications in live cells.

Basic Information

Product Name	17-Azido-3,6,9,12,15-Pentaoxaheptadecan-1-Amine
CAS No.	516493-93-9
Molecular Formula	C12H26N4O5
Molecular Weight	306.36 g/mol
Synonyms	Azido-PEG5-amine; 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine; N3-PEG5-NH2; Azido-PEG5-amine; 2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanamine; Amino-PEG5-azide; PEG5 bis-amine/azide; Azido-terminated PEG amine
EINECS	Contact for details

Quality Control

Every batch of 17-Azido-3,6,9,12,15-Pentaoxaheptadecan-1-Amine is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for research and pharmaceutical-grade intermediates. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and functional group integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. For long-term storage under an inert atmosphere (e.g., argon or nitrogen) is recommended to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details
Azide Content (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.