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(5-Bromo-2,3,4-Trifluorophenyl)Methanol CAS NO 511511-02-7
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CAS No.:511511-02-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(5-Bromo-2,3,4-Trifluorophenyl)Methanol is a high-value fluorinated aromatic building block characterized by its bromine and multiple fluorine substituents. This compound is essential for introducing specific steric and electronic properties into advanced molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates targeting CNS disorders, oncology, and anti-infectives.
- Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethylphenyl moiety enhances bioavailability and metabolic stability.
- Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
- Polymer & Resin Modifier: Incorporated as a functional monomer to impart specific properties like chemical resistance, thermal stability, and low surface energy to specialty polymers.
- Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
- Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel fluorinated compound libraries.
Basic Information
| Product Name | (5-Bromo-2,3,4-Trifluorophenyl)Methanol |
| CAS No. | 511511-02-7 |
| Molecular Formula | C7H3BrF3O |
| Molecular Weight | 239.00 g/mol |
| Synonyms | (5-Bromo-2,3,4-trifluorophenyl)methanol; 5-Bromo-2,3,4-trifluorobenzyl alcohol; 2,3,4-Trifluoro-5-bromobenzyl alcohol; (5-Bromo-2,3,4-trifluorophenyl)carbinol; α-Hydroxymethyl-5-bromo-2,3,4-trifluorobenzene; 5-Bromo-2,3,4-trifluoro-benzenemethanol; Benzenemethanol, 5-bromo-2,3,4-trifluoro- |
| EINECS | Contact for details |
Quality Control
Our (5-Bromo-2,3,4-Trifluorophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with global regulatory standards.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong bases and fluorides.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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