Description

2-Oxazolidinone, 3-[6-[2-[(2,6-Dichlorophenyl)Methoxy]Ethoxy]Hexyl]-5-(2,2-Dimethyl-4H-1, 3-Benzodioxin-6-Yl)-, (5R)- is a high-purity, chiral pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting infectious diseases. It is essential for research and development laboratories, process chemists, and manufacturers in the global pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for advanced drug synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and commercial-scale synthesis of novel antibiotic agents, particularly oxazolidinone-class antibiotics.
• API Development: Used as a key precursor in the development and optimization of synthetic routes for new chemical entities (NCEs) and generic active pharmaceutical ingredients.
• Process Chemistry & Scale-Up: Serves as a validated intermediate for process development, route scouting, and pilot-to-commercial scale manufacturing campaigns.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) and develop new antimicrobial compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules and clinical trial materials.
• Reference Standard: Can be utilized as a high-purity analytical reference standard for quality control and regulatory submissions.

Basic Information

Product Name	2-Oxazolidinone, 3-[6-[2-[(2,6-Dichlorophenyl)Methoxy]Ethoxy]Hexyl]-5-(2,2-Dimethyl-4H-1, 3-Benzodioxin-6-Yl)-, (5R)-
CAS No.	503068-36-8
Molecular Formula	C28H35Cl2NO6
Molecular Weight	552.49 g/mol
Synonyms	(5R)-3-[6-[2-[(2,6-Dichlorophenyl)Methoxy]Ethoxy]Hexyl]-5-(2,2-Dimethyl-4H-1,3-Benzodioxin-6-Yl)-2-Oxazolidinone; Radezolid Intermediate; RX-1741 Intermediate; (R)-3-(6-(2-((2,6-Dichlorobenzyl)oxy)ethoxy)hexyl)-5-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one; UNII-9V6A2X6Q6J; 9V6A2X6Q6J; Oxazolidinone antibiotic intermediate; Chiral oxazolidinone derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical pharmaceutical applications. Quality is verified through comprehensive analytical testing including HPLC for purity and chiral purity, NMR, and MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications. We support our partners in meeting the stringent requirements for GMP-grade intermediates and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.