Description

(E)-4-(Dimethylamino)But-2-Enoyl Chloride (Hydrochloride) is a versatile and reactive acid chloride derivative, primarily utilized as a key synthetic intermediate in advanced organic synthesis. Its value lies in its ability to introduce the (E)-4-(dimethylamino)but-2-enoyl moiety, a valuable building block for constructing complex molecules with specific functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the incorporation of an enoyl chloride functional group.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals where the dimethylaminoalkenoyl structure is required.
• Academic & R&D: A valuable reagent for medicinal chemistry and organic synthesis research in university and corporate laboratories.
• Peptide Mimetic Chemistry: Employed in the construction of peptide analogs and enzyme inhibitors due to its reactive acyl chloride group.
• Material Science Precursor: Potential use in the synthesis of monomers or functional agents for advanced polymeric materials.

Basic Information

Product Name	(E)-4-(Dimethylamino)But-2-Enoyl Chloride (Hydrochloride)
CAS No.	501332-27-0
Molecular Formula	C6H11Cl2NO
Molecular Weight	184.06 g/mol
Synonyms	(E)-4-(Dimethylamino)-2-butenoyl chloride hydrochloride; trans-4-(Dimethylamino)crotonoyl chloride hydrochloride; 4-(Dimethylamino)-2-butenoyl chloride, (E)-, hydrochloride; 2-Butenoyl chloride, 4-(dimethylamino)-, (E)-, hydrochloride; Crotonoyl chloride, 4-(dimethylamino)-, hydrochloride, (E)-; DMABC hydrochloride
EINECS	Contact for details

Quality Control

Our (E)-4-(Dimethylamino)But-2-Enoyl Chloride (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.