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4-Methylphenyl2-Azido-2-Deoxy-1-Thio-β-D-Glucopyranoside-3,4,6-Triacetate CAS NO 501088-45-5


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CAS No.:501088-45-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Methylphenyl2-Azido-2-Deoxy-1-Thio-β-D-Glucopyranoside-3,4,6-Triacetate is a sophisticated thioglycoside derivative, specifically designed as a key synthetic intermediate in advanced carbohydrate chemistry. Its core value lies in the strategic combination of an azido group and a thio-linked aglycone, which makes it a versatile building block for the synthesis of complex glycoconjugates and glycomimetics. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel drug candidates, diagnostic probes, and tools for studying carbohydrate-protein interactions.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel glycosidase inhibitors, antiviral agents, and carbohydrate-based therapeutics.
  • Glycoconjugate Synthesis: Used as a key building block for constructing complex oligosaccharides, glycopeptides, and glycolipids via chemoselective ligation strategies.
  • Chemical Biology & Probe Development: Enables the creation of activity-based probes (ABPs) and metabolic labeling agents for studying glycosylation pathways and enzyme functions.
  • Material Science: Serves as a monomer or functionalization agent for developing advanced biomaterials and glyco-functionalized surfaces with specific bio-recognition properties.
  • Agrochemical Research: Employed in the research and development of new carbohydrate-derived pesticides and plant growth regulators.
  • Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and glycoscience.

Basic Information

Product Name 4-Methylphenyl2-Azido-2-Deoxy-1-Thio-β-D-Glucopyranoside-3,4,6-Triacetate
CAS No. 501088-45-5
Molecular Formula C19H23N3O7S
Molecular Weight 437.47 g/mol
Synonyms p-Tolyl 2-azido-2-deoxy-1-thio-β-D-glucopyranoside 3,4,6-triacetate; 1-Thio-β-D-glucopyranoside, 2-azido-2-deoxy-, 3,4,6-triacetate, 4-methylphenyl; 2-Azido-2-deoxy-1-thio-β-D-glucopyranoside 3,4,6-triacetate p-tolyl ester; 4-Methylphenyl 2-azido-2-deoxy-1-thio-β-D-glucopyranoside triacetate; Azido-thioglycoside triacetate; Thioglycosyl donor with azido group; p-Tolyl 2-azido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside
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Quality Control

Our production of 4-Methylphenyl2-Azido-2-Deoxy-1-Thio-β-D-Glucopyranoside-3,4,6-Triacetate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or COA. This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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