Description

Toluene-4-Sulfonic Acid 6-Azidohexyl Ester is a specialized bifunctional chemical building block that combines a reactive sulfonate ester group with a versatile azido moiety. This unique structure makes it a critical intermediate for click chemistry applications, particularly in the synthesis of complex molecules and functional materials. It is primarily utilized by researchers and manufacturers in pharmaceutical development, bioconjugation, and polymer science to create novel drug candidates, diagnostic probes, and advanced polymeric networks.

Application

• Click Chemistry Reagent: Serves as a key precursor for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to build molecular architectures.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring targeted functionalization.
• Bioconjugation Linker: Facilitates the covalent attachment of dyes, drugs, or other molecules to proteins, antibodies, or nanoparticles for diagnostic and therapeutic applications.
• Polymer Modification: Enables the introduction of azide groups into polymer backbones or surfaces for subsequent cross-linking or grafting.
• Material Science: Employed in the development of functional coatings, hydrogels, and smart materials with tailored properties.
• Chemical Biology Probe Synthesis: Used to create activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Product Name	Toluene-4-Sulfonic Acid 6-Azidohexyl Ester
CAS No.	500567-77-1
Molecular Formula	C13H19N3O3S
Molecular Weight	297.37 g/mol
Synonyms	6-Azidohexyl 4-methylbenzenesulfonate; p-Toluenesulfonic acid 6-azidohexyl ester; 4-Methylbenzenesulfonic acid 6-azidohexyl ester; 6-Azidohexyl tosylate; Tosyl 6-azidohexyl ester; Azido-PEG6-tosylate; 6-Azido-1-hexanol tosylate; 1-Azido-6-(tosyloxy)hexane
EINECS	Contact for details

Quality Control

Our Toluene-4-Sulfonic Acid 6-Azidohexyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and spectral identification are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to the presence of the azide functional group, appropriate safety protocols for handling azide compounds should be followed.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.