Description

Thienamycin is a potent, broad-spectrum β-lactam antibiotic belonging to the carbapenem class, representing a significant advancement in antibacterial therapy. Its unique chemical structure provides exceptional stability against many β-lactamase enzymes, making it a crucial compound for research into overcoming antibiotic resistance. This high-purity material is essential for pharmaceutical R&D, analytical reference standards, and the synthesis of novel antibiotic derivatives. Global suppliers and research institutions rely on consistent quality and reliable supply chains for this critical intermediate.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate and reference standard in the development of new carbapenem-class antibiotics.
• Antibacterial Mechanism Studies: Used in biochemical and microbiological research to study β-lactamase inhibition and bacterial cell wall synthesis.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.
• Synthetic Chemistry: Acts as a sophisticated building block for the chemical synthesis of novel antibiotic analogs and derivatives with potentially enhanced properties.
• Academic & Institutional Research: Fundamental research tool in university and government labs focused on medicinal chemistry and infectious disease.

Basic Information

Product Name	Thienamycin
CAS No.	59995-64-1
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	(5R,6S)-3-[(2S)-2-Amino-2-carboxyethyl]sulfanyl-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[(2S)-2-amino-2-carboxyethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Antibiotic MK 0787; N-Acetylthienamycin; N-Formimidoylthienamycin (precursor); Thienamycin free acid
EINECS	Contact for details

Quality Control

Our Thienamycin is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including HPLC for assay and purity, and is accompanied by a detailed Certificate of Analysis (COA). We support compliance with cGMP guidelines for pharmaceutical intermediates and can provide material suitable for use as a certified reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.