Description

S-(N(6),N(6)-Dimethyladenosyl)Methionine is a specialized, high-purity biochemical compound, also known as a dimethylated derivative of S-adenosylmethionine (SAMe). This molecule is critical as a methyl group donor in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying epigenetic regulation, enzyme kinetics, and as a potential precursor in novel therapeutic agents.

Application

• Biochemical Research: As a key reagent in enzymatic studies, particularly those involving methyltransferase activity and epigenetic mechanisms.
• Pharmaceutical Intermediates: Serves as a sophisticated building block or precursor in the synthesis of novel drug candidates targeting neurological and metabolic pathways.
• Enzyme Substrate: Used in high-throughput screening (HTS) assays to discover and characterize new methyltransferase inhibitors for drug discovery.
• Metabolomics & Diagnostic Development: Employed as a reference standard in mass spectrometry and chromatography for quantifying metabolic pathways in clinical research.
• Academic Research: Fundamental tool in university and institutional labs for investigating cellular signaling, one-carbon metabolism, and gene expression control.

Basic Information

Product Name	S-(N(6),N(6)-Dimethyladenosyl)Methionine
CAS No.	59987-54-1
Molecular Formula	C17H26N6O5S+
Molecular Weight	426.50 g/mol
Synonyms	S-Adenosyl-L-methionine, N(6),N(6)-dimethyl-; Dimethyl-SAM; N6,N6-Dimethyl-S-adenosyl-L-methionine; S-(5'-Deoxyadenosin-5'-yl)-L-methionine, N(6),N(6)-dimethyl-; AdoMet dimethyl derivative; SAMe dimethyl derivative; 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-N6,N6-dimethyladenosine
EINECS	Contact for details

Quality Control

Our S-(N(6),N(6)-Dimethyladenosyl)Methionine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade and potential cGMP guidelines for non-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.