Description

S-3'-Deoxyadenosylmethionine is a biologically significant sulfonium compound, a structural analog of the universal methyl donor S-adenosylmethionine (SAMe). This specialized molecule is valued for its role in biochemical research and development, particularly in studies of methylation pathways and enzyme mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in metabolic studies, drug discovery, and the synthesis of novel biochemical tools.

Application

• Biochemical Research: As a key reference standard and substrate in enzymatic studies, particularly for methyltransferases and other SAMe-dependent enzymes.
• Pharmaceutical Development: Investigation into novel therapeutic agents targeting methylation-related disorders and metabolic pathways.
• Metabolomics & Diagnostic Research: Used as a calibrant or internal standard in advanced analytical techniques like LC-MS/MS for quantifying related metabolites in biological samples.
• Enzyme Mechanism Studies: Probing the structure-activity relationships and catalytic mechanisms of enzymes that utilize adenosylmethionine derivatives.
• Synthesis of Biochemical Probes: Serving as a precursor or building block for the development of labeled compounds (e.g., isotopically labeled) for tracer studies.

Basic Information

Product Name	S-3'-Deoxyadenosylmethionine
CAS No.	59987-48-3
Molecular Formula	C15H23N6O5S+
Molecular Weight	399.45 g/mol
Synonyms	S-3'-Deoxyadenosyl-L-methionine; 3'-Deoxy-S-adenosylmethionine; 3'-Deoxy-AdoMet; 5'-Deoxy-5'-(3-deoxyadenosin-5'-yl)-L-methionine; S-(5'-Deoxy-3'-adenosyl)-L-methionine; 3'-dAdoMet; 3'-Deoxy-SAMe
EINECS	Contact for details

Quality Control

Our S-3'-Deoxyadenosylmethionine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay results, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Anion Content)	Contact for details
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.