Description

44-o-Demethylthiocillin Ii is a thiopeptide antibiotic compound, a derivative of the thiocillin family. This molecule is of significant interest in pharmaceutical research and development due to its potent antibacterial activity, particularly against Gram-positive pathogens. It serves as a critical intermediate and reference standard for researchers in the fields of medicinal chemistry, antibiotic discovery, and microbiology. The compound is identified by the CAS registry number 59979-01-0.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel antibiotic agents and for structure-activity relationship (SAR) studies.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related thiopeptide antibiotics.
• Microbiological Studies: Employed in in vitro assays to investigate mechanisms of action and resistance against bacterial targets.
• Medicinal Chemistry: Serves as a scaffold for the design and synthesis of new derivatives with improved pharmacological properties.
• Academic Research: Utilized in university and institutional labs for fundamental research on antibiotic biosynthesis and mode of action.

Basic Information

Product Name	44-o-Demethylthiocillin Ii
CAS No.	59979-01-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	44-O-Demethylthiocillin II; Demethylthiocillin II; Thiocillin derivative; Antibiotic GE2270 derivative; Thiopeptide antibiotic intermediate; [Additional synonyms available upon request]
EINECS	Contact for details

Quality Control

Our 44-o-Demethylthiocillin Ii is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.