Description

(22S,25S)-5α-Spirostane-3β,25-Diol CAS NO 59951-78-9 is a high-purity, stereochemically defined spirostane derivative, a key intermediate in the synthesis of bioactive steroids and sapogenins. Its precise stereochemistry at the 22 and 25 positions makes it a critical building block for pharmaceutical research and development, ensuring consistent outcomes in complex synthetic pathways. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents and plant growth regulators.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of steroidal drugs, including certain cardiac glycosides and hormone analogs.
• Biochemical Research: Used as a reference standard and probe in studies of steroid biosynthesis, metabolism, and receptor interactions.
• Agrochemical Development: Serves as a starting material for creating novel plant growth regulators and eco-friendly pesticides based on natural product structures.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and other high-value specialty chemicals.
• Reference Material: Utilized in analytical laboratories for method development and quality control of steroidal compounds.

Basic Information

Item	Detail
Product Name	(22S,25S)-5α-Spirostane-3β,25-Diol
CAS No.	59951-78-9
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	5α-Spirostane-3β,25-diol, (22S,25S)-; (22S,25S)-5α-Spirostan-3β,25-diol; 3β,25-Dihydroxy-5α-spirostane; Tigogenin-3β,25-diol; (25S)-5α-Spirostane-3β,25-diol; 25S-Spirostane-3β,25-diol; Diosgenin derivative; Spirostanediol
EINECS	Contact for details

Quality Control

Every batch of (22S,25S)-5α-Spirostane-3β,25-Diol is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (22S,25S)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.