Description

Doconazole CAS NO 59831-63-9 is a potent imidazole-class antifungal agent. This compound is valued for its broad-spectrum activity against a wide range of pathogenic fungi and yeasts, making it a critical active pharmaceutical ingredient (API). It is primarily utilized by the pharmaceutical industry for the formulation of topical and systemic antifungal medications. Its efficacy and stability profile support its use in developing treatments for various fungal infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription antifungal creams, ointments, and oral formulations.
• Topical Antifungals: Formulation into treatments for skin infections such as athlete's foot, ringworm, and candidiasis.
• Systemic Antifungal Therapy: Development of oral or injectable medications for treating severe internal fungal infections.
• Veterinary Medicine: Incorporation into antifungal treatments for animals.
• Agricultural Fungicide: Potential use in protecting crops from fungal diseases, subject to regional regulatory approval.
• Research & Development: Serving as a reference standard and a key intermediate in synthesizing novel antifungal agents.

Basic Information

Product Name	Doconazole
CAS No.	59831-63-9
Molecular Formula	C18H14Cl3N3O
Molecular Weight	394.68 g/mol
Synonyms	Doconazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; R-34000; (±)-Doconazole; Doconazol; Doconazolum
EINECS	Contact for details

Quality Control

Our Doconazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure it meets high-purity pharmaceutical standards. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.