Description

3-Pyridinecarbonyl Chloride, 1,2,5,6-Tetrahydro-1-Methyl- (9Ci) is a specialized heterocyclic building block and acid chloride derivative of significant interest in advanced organic synthesis. This compound matters for its role as a key reactive intermediate, enabling the efficient introduction of a functionalized nicotinoyl moiety into target molecules. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or binding properties.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 1,2,5,6-Tetrahydro-1-Methyl- (9Ci)
CAS No.	59826-28-7
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	1-Methyl-1,2,5,6-tetrahydronicotinoyl chloride; 1-Methyl-3-piperidinecarbonyl chloride; 1-Methyl-1,2,5,6-tetrahydropyridine-3-carbonyl chloride; 3-Carbonyl chloride-1-methyl-1,2,5,6-tetrahydropyridine; 1-Methyl-3-(chlorocarbonyl)-1,2,5,6-tetrahydropyridine; N-Methyl-δ³-piperideine-3-carbonyl chloride; 1-Methyl-1,2,5,6-tetrahydronicotinic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 1,2,5,6-Tetrahydro-1-Methyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for research and process development. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.