Description

3-Pyridinecarbonyl Chloride, 5-(Acetylamino)- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling precise molecular construction for complex target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Peptide Mimetics and Bioconjugation: The reactive acid chloride group is utilized for coupling reactions to create peptide analogs or for bioconjugation strategies.
• Academic and R&D Laboratories: A valuable reagent for methodological studies and exploring new chemical transformations in heterocyclic chemistry.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 5-(Acetylamino)- (9Ci)
CAS No.	59793-45-2
Molecular Formula	C8H7ClN2O2
Molecular Weight	198.61 g/mol
Synonyms	5-Acetamidonicotinoyl Chloride; 5-Acetamidopyridine-3-carbonyl Chloride; 3-Carbamoyl-5-acetamidopyridine Hydrochloride (related salt); 5-Acetylaminonicotinic Acid Chloride; 5-(Acetylamino)nicotinoyl Chloride; 5-Acetamido-3-pyridinecarbonyl Chloride; N-(5-(Chlorocarbonyl)pyridin-3-yl)acetamide
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 5-(Acetylamino)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for specific impurities. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.