Description

Guanosine 5'-(Trihydrogen Diphosphate), Trisodium Salt is a high-purity nucleotide derivative, specifically the trisodium salt of guanosine 5'-diphosphate (GDP). This compound is a critical biochemical reagent and building block for enzymatic synthesis and research. It is essential for researchers and manufacturers in the fields of molecular biology, pharmaceutical development, and diagnostic assay production. The product is supplied as a high-quality, well-characterized material to ensure reliable and reproducible results in sensitive applications.

Application

• Biochemical Research & Enzymology: Serves as a substrate or cofactor for kinases, polymerases, and other nucleotide-dependent enzymes in mechanistic studies and enzyme activity assays.
• Pharmaceutical Intermediates: Used in the synthesis of nucleotide-based prodrugs, antiviral agents, and other therapeutic compounds targeting cellular signaling pathways.
• Diagnostic Kit Manufacturing: A key component in the formulation of reagents for diagnostic tests, including ELISA and other assays that rely on enzymatic signal amplification.
• Cell Culture & Metabolism Studies: Employed in media supplements and research to study cellular energy metabolism, signal transduction, and purine biosynthesis pathways.
• Molecular Biology Reagents: Acts as a precursor for the synthesis of modified nucleotides, labeled probes, and other tools for genomics and proteomics research.

Basic Information

Product Name	Guanosine 5'-(Trihydrogen Diphosphate), Trisodium Salt
CAS No.	59652-27-6
Molecular Formula	C10H12N5Na3O11P2
Molecular Weight	529.14 g/mol
Synonyms	GDP Trisodium Salt; Guanosine 5'-Diphosphate Trisodium Salt; Sodium Guanosine 5'-Diphosphate; 5'-GDP Trisodium; Disodium Guanosine 5'-(Trihydrogen Diphosphate) Monosodium Salt; Guanosine-5'-diphosphoric acid trisodium salt; Trisodium guanosine-5'-diphosphate
EINECS	Contact for details

Quality Control

Our Guanosine 5'-(Trihydrogen Diphosphate), Trisodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with detailed results to ensure traceability and compliance with your research or production standards. The product is suitable for use in GMP-controlled environments upon request and agreement of specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For extended storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (5% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.