Description

(+)-Axisothiocyanate 3 CAS NO 59633-81-7 is a high-purity, chiral thiocyanate derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile chiral building block and intermediate, enabling the stereoselective construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where the specific enantiomer can influence biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways due to its reactive thiocyanate group.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of chiral flavor and aroma compounds.

Basic Information

Item	Details
Product Name	(+)-Axisothiocyanate 3
CAS No.	59633-81-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(+)-Axisothiocyanate III; (R)-Axisothiocyanate 3; Axisothiocyanate 3, (+)-; 1-(1,3-Benzodioxol-5-yl)-2-(methylsulfonyl)ethan-1-one oxime; CAS 59633-81-7; (R)-1,3-Benzodioxol-5-yl)[(methylsulfonyl)acetyl] ketoxime thiocyanate; (R)-N-Hydroxy-2-(methylsulfonyl)-1-(3,4-methylenedioxyphenyl)ethan-1-imine thiocyanate
EINECS	Contact for details

Quality Control

Our (+)-Axisothiocyanate 3 is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, identity confirmation by IR and NMR spectroscopy, and determination of residual solvents. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.